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Maharashtra Detects 91 Cases of New 'FLiRT' Covid-19 Variant: Comprehensive Overview

Maharashtra's identification of 91 cases of the FLiRT variant of Covid-19 underscores the emergence of a new strain with potential implications for transmission and vaccine effectiveness 

16-05-2024
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In Maharashtra, a notable increase in Covid-19 cases linked to the Omicron subvariant KP.2 has been reported. According to Times of India, Pune has the highest count with 51 cases, followed closely by Thane with 20 cases. Other regions like Amravati, Aurangabad, Solapur, Ahmednagar, Nashik, Larur, and Sangli have also recorded cases, but Mumbai has not reported any so far. Dr. Rajesh Karyakarte, the state's genome sequencing coordinator, highlighted the rise in cases but noted no significant surge in severe illness or hospitalizations.

The KP.2 variant, identified in January, has gained dominance, surpassing the previously prevalent JN.1 variant by March and April. Economic Times reported that the variant originated from the JN.1 strain and saw a minor rise in cases in March, averaging around 250 detections.

The FLiRT variant, encompassing KP.1.1 and KP.2 strains, has garnered attention globally since January. Japanese researchers identified specific mutations in the S protein of the KP.2 variant, indicating higher transmission rates compared to JN.1. Surprisingly, despite its higher reproduction number, KP.2 exhibits lower infectivity than JN.1.

In the United States, KP.2 has become prominent, representing 28% of Covid cases, while KP.1.1 accounts for only 7.1%. Concerns have arisen regarding vaccine effectiveness against KP.2, particularly for individuals previously infected with JN.1 and those vaccinated with XBB.1.5. However, vaccines still offer some protection, especially against severe illness.

The CDC has not found evidence suggesting that KP.2 leads to more severe illness, but certain groups remain more vulnerable. Symptoms of KP.2 and JN.1 variants mirror those of other strains, including sore throat, runny nose, coughing, body aches, fever, congestion, fatigue, and in some cases, shortness of breath. Additionally, gastrointestinal symptoms like diarrhea, nausea, and vomiting have been reported.

To combat the spread of Covid-19, adherence to preventive measures such as wearing masks, maintaining hand hygiene, practicing social distancing, avoiding large gatherings and poorly ventilated spaces, cleaning frequently touched surfaces, staying home when sick, following local guidelines, and supporting vaccination efforts is crucial. These measures can significantly reduce the risk of virus transmission.

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